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Главная Новости Рекомендации по эндоскопическому лечению пациентов с дисплазией и внутрислизистым раком при пищеводе Баррета.

Новости: Рекомендации по эндоскопическому лечению пациентов с дисплазией и внутрислизистым раком при пищеводе Баррета.

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Баррет Алгоритм_lrg.jpg


Американское общество гастроинтестинальной эндоскопии предлагает ознакомиться с новыми рекомендациями по эндоскопическому лечению пациентов с дисплазией и внутрислизистым раком при пищеводе Баррета.

Пищевод барретта (BE) определяется заменой нормального плоскоклеточного эпителия дистального пищевода метапластическим столбчатым эпителием кишечного типа.

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Endoscopic eradication therapy for patients with Barrett’s esophagus–associated dysplasia and intramucosal cancer

Prepared by: Standards of Practice Committee, Sachin Wani, MD∗; Bashar Qumseya, MD, MPH∗; Shahnaz Sultan, MD; Deepak Agrawal, MD; Vinay Chandrasekhara, MD; Ben Harnke, PhD; Shivangi Kothari, MD; Martin McCarter, MD; Aasma Shaukat, MD, MPH; Amy Wang, MD; Julie Yang, MD; John Dewitt, MD

Abstract

Barrett’s esophagus (BE) is defined by the replacement of the normal squamous epithelium of the distal esophagus with metaplastic intestinal-type columnar epithelium.1-3 BE is an adverse event of chronic GERD and the only identifiable premalignant condition for esophageal adenocarcinoma (EAC), a cancer that continues to increase in incidence. In 2014 there were approximately 18,170 incident cases of esophageal cancer in the United States, nearly 60% of which were EAC.4-6 Although uncommon, EAC is a highly lethal cancer associated with a poor 5-year survival rate of 15% to 20% and an overall median survival of <1 year in cases with advanced disease.

Источник: GIEjournal

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(злокачественное малокровие, пернициозная анемия, в12-дефицитная анемия) B12 анемия, обусловленная аутоимунными механизмами, сопровождается ахилией, отсутствие пепсина и продукцией антител к париетальным клеткам.Гастроскопия выявляет гнездную, ре­же тотальную атрофию слизистой желудкаХарактерным симптомом является наличие так называемых перламутровых бляшек — блестящих зеркальных участков атрофии слизистой, локализующихся главным обра­зом на складках слизистой желудка.

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